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Saturday, 10 November 2012 12:51
It is with great sadness that we announce the passing of Rita Becker beloved wife, mother, grandmother, and great grandmother on Thursday November 8, 2012 at the age of 84.
Those left to cherish her memory are Ron Becker her loving husband of 62 years and her three children Gary (Ann) Becker, their children Jared and Sarah, Donna (Rob) Coleman, their children Jeremy and Kristie (Kane Buck), David (Janet) Becker, and their child Jolene Lebsack (John Ross) and great granddaughters Brooke and Hadleigh Coleman. She also leaves behind her sisters Kay Hirsche, Pat Whitlock, Lil Brandley and Arline Iredale, sister-in-law Muriel Sparks, and numerous nieces and nephews. Rita was predeceased by her parents Fred and Doris Sparks, brother Morgan Sparks, and four bothers-in-law Gerald Hirsche, Dick Brandley, Jack Iredale and Colin Whitlock. Rita was born December 11, 1927, in Taber, AB the second child of six to Fred and Doris Sparks. Rita completed her education in Taber and started her career at the Bank of Montreal. Ron and Rita moved to Lethbridge in 1966 after Ron accepted a position at the Lethbridge Junior College. Rita started a long career at the University of Lethbridge in the Controller’s office in 1967 and retired after 22 years in 1989. Rita enjoyed their many camping trips with family and friends and trips to California to see her sisters and families. She was a faithful fan at all her grandchildren’s sporting events. Rita was a loving and devoted wife, mother, grandmother and great grandmother and will be dearly missed. A Celebration of Life will be held at 1:00 pm, on Monday, November 12, 2012 MARTIN BROTHERS FUNERAL CHAPELS, 610 – 4 Street South, Lethbridge. Send condolences at www.mbfunerals.com. Martin Bros. Funeral Chapels Ltd. 610 - 4 Street South Lethbridge, AB T1J 4P3 Phone: (403)328-2361 Fax: (403)382-3623 Toll Free: 1-800-382-2901 www.mbfunerals.com
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Portions of the above information has been provided by the National Institutes of Health
Researchers Stacy Mandras and Mandeep Mehra conducted a meta-analysis of studies of sexual activity in men with coronary artery disease. They found that in middle-aged men both with and without such disease, the increases in heart rate, blood pressure and respiratory rate were well within the safe range. The highest heart rate during sexual intercourse, in fact, was actually lower than the maximum heart rate achieved simply in the course of daily activity.
Sildenafil was recently studied in a large series of diabetic men with erectile dysfunction and was found to be well tolerated and effective.22 In this randomized, controlled trial, 74 of 131 patients taking sildenafil reported improved erections compared with only 13 of 127 patients taking a placebo. The incidence of mild adverse effects was higher in the group taking sildenafil, but the incidence of cardiovascular events was similar in both groups.
Erectile dysfunction is increasingly being recognized as a common, treatable disorder. The development of sildenafil has prompted an unprecedented number of men to seek treatment. Sildenafil may not be appropriate for all patients, but other therapeutic options discussed in this article may be of benefit. A thoughtful evaluation may reveal treatable causes and provide family physicians with an opportunity to become involved in the comprehensive health care of men who otherwise would not have sought medical attention.
Erectile Dysfunction: Lifestyle Changes to Improve ED
Erectile Dysfunction: Penile Prosthesis
Hypertension, or high blood pressure, is closely linked to erectile dysfunction. Research shows that between 35 and 58 percent of men with hypertension had ED compared to only 14.1 percent of men with normal pressure.
Other men prefer to undergo surgery for the insertion of a penile implant. The simplest and most durable of these is a flexible rod that allows the penis to be folded away when not in use. Other men prefer a fluid-filled implant that lets them pump the penis erect.
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The medication, in addition to its use as a popular treatment for impotence, has already been approved by the U.S. Food and Drug Administration for the treatment of the chronic version of such blood pressure spikes, known as pulmonary arterial hypertension (PAH). The drug has been marketed specifically for this purpose under the trade name Revatio. Another drug -- bosentan -- is also approved for similar purposes.
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Almost immediately after the discovery of cAMP by Sutherland and colleagues, cyclic nucleotide PDE activity was described (Butcher and Sutherland, 1962). With the subsequent discovery of cGMP, it was found that both cAMP and cGMP could be hydrolyzed by the same type of activity, i.e., hydrolysis of the 3? cyclic phosphate bond. On the basis of substrate competition studies, it was clear that at least some of these activities must have the same catalytic site. In fact, many of the early studies on cyclic nucleotides were directed toward understanding PDE activity since at that time it was much easier to measure PDE activity than either cAMP or cGMP themselves or the enzymes that catalyzed their synthesis. With the advent of assays using radioactive substrate, it became clear that there were likely to be multiple forms of PDEs with different kinetic and regulatory properties (Thompson et al., 1979; Beavo et al., 1982). However, it was not until higher resolution fractionation techniques, monoclonal antibodies, and molecular cloning and sequencing procedures were applied to the PDEs that the truly large number of different gene products was fully appreciated.
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